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Summary
In the present study, some haematological indices and
histopathological changes were investigated in male zebu calves naturally
infected with Onchocerca gutturosa (O.guttursosa), and medicated with either
Ivermectin, Chloroquine or Artemether. Their administration had no
significant effect on Haemoglobin concentration (Hb %), packed cell volume
(PCV) and total white blood cells (WBCs) count (P>0.05). However, there was
an increase in the circulating eosinophils due to the death of microfilariae
(mf) following treatments. Sections of skin before treatment revealed active
cellular reactions due to the presence of microfilariae. These reactions were
more intense after treatment and the subsequent death of dermal mf. No
adverse side effects were observed in the treated calves.

 
 
   
 
 

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