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Summary The antimicrobial susceptibility reactions of 12 Mannheimia haemolytica and 8 Pasteurella multocida isolates from pneumonic sheep ,collected from Al-Damazin slaughterhouse, the Blue Nile State, Sudan, were evaluated by disk diffusion method. Each isolate was tested against ciprofloxacin, ceftriaxone, cefuroxime, chloramphenicol, ampicillin, gentamicin, co-trimoxazole and tetracycline. All isolates of the two species were sensitive to ciprofloxacin, ceftriaxone, cefuroxime and 90% of them were sensitive to chloramphenicol and ampicillin. Seventy - five per cent (9/12) of M. haemolytica isolates were resistant to gentamicin and co-trimoxazole. Fifty per cent (4/8) of P. multocida isolates were sensitive to tetracycline whereas 87.5% (7/8) of them were resistant to gentamicin and 62.5% (5/8) to co-trimoxazole.

 
 
   
 
 

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